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Escherichia coli Dihydropyrimidine Dehydrogenase Is a Novel NAD-Dependent Heterotetramer Essential for the Production of 5,6-Dihydrouracil

The reductive pyrimidine catabolic pathway is absent in Escherichia coli. However, the bacterium contains an enzyme homologous to mammalian dihydropyrimidine dehydrogenase. Here, we show that E. coli dihydropyrimidine dehydrogenase is the first member of a novel NADH-dependent subclass of iron-sulfu...

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Bibliografiset tiedot
Päätekijät: Hidese, Ryota, Mihara, Hisaaki, Kurihara, Tatsuo, Esaki, Nobuyoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028684/
https://ncbi.nlm.nih.gov/pubmed/21169495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01178-10
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