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Circadian rhythm of dihydrouracil/uracil ratios in biological fluids: a potential biomarker for dihydropyrimidine dehydrogenase levels

1. In many cancer patients, 5-fluorouracil (5-FUra) treatment is toxic and even causes death. Nevertheless, all patients are subjected to a standard therapy regimen because there is no reliable way to identify beforehand those patients who are predisposed to 5-FUra-induced toxicity. In this study, w...

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Detalhes bibliográficos
Main Authors: Jiang, Hao, Lu, Jing, Ji, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574234/
https://ncbi.nlm.nih.gov/pubmed/14744810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705651
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