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Escherichia coli Dihydropyrimidine Dehydrogenase Is a Novel NAD-Dependent Heterotetramer Essential for the Production of 5,6-Dihydrouracil

The reductive pyrimidine catabolic pathway is absent in Escherichia coli. However, the bacterium contains an enzyme homologous to mammalian dihydropyrimidine dehydrogenase. Here, we show that E. coli dihydropyrimidine dehydrogenase is the first member of a novel NADH-dependent subclass of iron-sulfu...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Hidese, Ryota, Mihara, Hisaaki, Kurihara, Tatsuo, Esaki, Nobuyoshi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028684/
https://ncbi.nlm.nih.gov/pubmed/21169495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01178-10
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