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La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability

The conserved RNA binding protein La recognizes UUU-3′OH on its small nuclear RNA ligands and stabilizes them against 3′-end-mediated decay. We report that newly described La-related protein 4 (LARP4) is a factor that can bind poly(A) RNA and interact with poly(A) binding protein (PABP). Yeast two-h...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Ruiqing, Gaidamakov, Sergei A., Xie, Jingwei, Lee, Joowon, Martino, Luigi, Kozlov, Guennadi, Crawford, Amanda K., Russo, Amy N., Conte, Maria R., Gehring, Kalle, Maraia, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028612/
https://ncbi.nlm.nih.gov/pubmed/21098120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01162-10
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