Smad3 Deficiency in Mice Protects Against Insulin Resistance and Obesity Induced by a High-Fat Diet

OBJECTIVE: Obesity and associated pathologies are major global health problems. Transforming growth factor-β/Smad3 signaling has been implicated in various metabolic processes, including adipogenesis, insulin expression, and pancreatic β-cell function. However, the systemic effects of Smad3 deficien...

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Main Authors: Tan, Chek Kun, Leuenberger, Nicolas, Tan, Ming Jie, Yan, Yew Wai, Chen, Yinghui, Kambadur, Ravi, Wahli, Walter, Tan, Nguan Soon
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2011
Fag:
Obesity Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028346/
https://ncbi.nlm.nih.gov/pubmed/21270259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0801
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