Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts

TGF-β and myostatin are the two most important regulators of muscle growth. Both growth factors have been shown to signal through a Smad3-dependent pathway. However to date, the role of Smad3 in muscle growth and differentiation is not investigated. Here, we demonstrate that Smad3-null mice have dec...

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Detalhes bibliográficos
Main Authors: Ge, Xiaojia, McFarlane, Craig, Vajjala, Anuradha, Lokireddy, Sudarsanareddy, Ng, Zhi Hui, Tan, Chek Kun, Tan, Nguan Soon, Wahli, Walter, Sharma, Mridula, Kambadur, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364732/
https://ncbi.nlm.nih.gov/pubmed/21502976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.72
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