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Laboratory and clinical evaluation of conjugate vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides bound to Pseudomonas aeruginosa recombinant exoprotein A.

The synthesis, standardization, and immunogenicity in young outbred mice and clinical evaluation in adult volunteers of investigational vaccines designed to induce serum antibodies to the type 5 and type 8 capsular polysaccharides (CPs) of Staphylococcus aureus are described. Conjugates composed of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Fattom, A, Schneerson, R, Watson, D C, Karakawa, W W, Fitzgerald, D, Pastan, I, Li, X, Shiloach, J, Bryla, D A, Robbins, J B
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8432585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.3.1023-1032.1993
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