Synthesis and immunologic properties in mice of vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides conjugated to Pseudomonas aeruginosa exotoxin A.

Epidemiological, serological and in vitro phagocytosis experiments provide evidence that the newly discovered type 5 and type 8 capsular polysaccharides (CPs) are both virulence factors and protective antigens for bacteremia caused by Staphylococcus aureus. Neither type 5 nor type 8 CP elicited seru...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Fattom, A, Schneerson, R, Szu, S C, Vann, W F, Shiloach, J, Karakawa, W W, Robbins, J B
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2114365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.7.2367-2374.1990
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