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Laboratory and clinical evaluation of conjugate vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides bound to Pseudomonas aeruginosa recombinant exoprotein A.

The synthesis, standardization, and immunogenicity in young outbred mice and clinical evaluation in adult volunteers of investigational vaccines designed to induce serum antibodies to the type 5 and type 8 capsular polysaccharides (CPs) of Staphylococcus aureus are described. Conjugates composed of...

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Publicat a:Infect Immun
Autors principals: Fattom, A, Schneerson, R, Watson, D C, Karakawa, W W, Fitzgerald, D, Pastan, I, Li, X, Shiloach, J, Bryla, D A, Robbins, J B
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8432585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.3.1023-1032.1993
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