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Endogenous and exogenous glucocorticoids have different roles in modulating endotoxin lethality in D-galactosamine-sensitized mice.

Endotoxin sensitivity and dexamethasone protection have been assessed in mice that were adrenalectomized and also treated with D-galactosamine at the time of endotoxin challenge. Our data establish that adrenalectomy did not detectably alter the magnitude of the increased sensitivity induced by D-ga...

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Detalhes bibliográficos
Main Authors: Gonzalez, J C, Johnson, D C, Morrison, D C, Freudenberg, M A, Galanos, C, Silverstein, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC302827/
https://ncbi.nlm.nih.gov/pubmed/8432617
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