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Growing tumors induce hypersensitivity to endotoxin and tumor necrosis factor.

Lewis lung carcinoma and EMT6 sarcoma growing as solid tumors in mice caused a gradual increase in the susceptibility of the animals to lethal toxicity of endotoxins (lipopolysaccharides [LPS]). By day 15 following inoculation of the tumors, the 50% lethal dose of LPS, which in normal mice was appro...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Bartholeyns, J, Freudenberg, M, Galanos, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3623699/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.9.2230-2233.1987
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