Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant

The HIV-1 envelope glycoproteins (Env) gp120 and gp41 mediate entry and are the targets for neutralizing antibodies. Within gp41, a continuous epitope defined by the broadly neutralizing antibody 2F5, is one of the few conserved sites accessible to antibodies on the functional HIV Env spike. Recentl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Guenaga, Javier, Dosenovic, Pia, Ofek, Gilad, Baker, David, Schief, William R., Kwong, Peter D., Karlsson Hedestam, Gunilla B., Wyatt, Richard T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027617/
https://ncbi.nlm.nih.gov/pubmed/21297864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016074
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi