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Quality of Original and Biosimilar Epoetin Products

PURPOSE: To compare the quality of therapeutic erythropoietin (EPO) products, including two biosimilars, with respect to content, aggregation, isoform profile and potency. METHODS: Two original products, Eprex (epoetin alfa) and Dynepo (epoetin delta), and two biosimilar products, Binocrit (epoetin...

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Dettagli Bibliografici
Autori principali: Brinks, Vera, Hawe, Andrea, Basmeleh, Abdul H. H., Joachin-Rodriguez, Liliana, Haselberg, Rob, Somsen, Govert W., Jiskoot, Wim, Schellekens, Huub
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026707/
https://ncbi.nlm.nih.gov/pubmed/20886265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0288-2
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