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High fat diet-induced obesity and heart dysfunction is regulated by the TOR pathway in Drosophila
High Fat Diet (HFD)-induced obesity is a major contributor to diabetes and cardiovascular disease, but the underlying genetic mechanisms are poorly understood. Here, we use Drosophila to test the hypothesis that HFD-induced obesity and associated cardiac complications have early evolutionary origins...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026640/ https://ncbi.nlm.nih.gov/pubmed/21035763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.09.014 |
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