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High fat diet-induced obesity and heart dysfunction is regulated by the TOR pathway in Drosophila

High Fat Diet (HFD)-induced obesity is a major contributor to diabetes and cardiovascular disease, but the underlying genetic mechanisms are poorly understood. Here, we use Drosophila to test the hypothesis that HFD-induced obesity and associated cardiac complications have early evolutionary origins...

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Hlavní autoři: Birse, Ryan T., Choi, Joan, Reardon, Kathryn, Rodriguez, Jessica, Graham, Suzanne, Diop, Soda, Ocorr, Karen, Bodmer, Rolf, Oldham, Sean
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026640/
https://ncbi.nlm.nih.gov/pubmed/21035763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.09.014
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