Effect of immunoglobulin G (IgG) interchain disulfide bond cleavage on efficacy of intravenous immunoglobulin for immune thrombocytopenic purpura (ITP)

Intravenous immunoglobulin (IVIG) has been used widely to treat immune thrombocytopenic purpura (ITP), but the mechanisms of its action remain unclear. We investigated the affinity for Fcγ receptors (FcγRs) and the thrombocytopenia-ameliorating effect of S-sulfonated gammaglobulin (SGG) and S-alkyla...

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Bibliografiske detaljer
Main Authors:	Machino, Y, Ohta, H, Suzuki, E, Higurashi, S, Tezuka, T, Nagashima, H, Kohroki, J, Masuho, Y
Format:	Artigo
Sprog:	Inglês
Udgivet:	Blackwell Science Inc 2010
Fag:	Translational Studies
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3026545/ https://ncbi.nlm.nih.gov/pubmed/21029072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04255.x
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Effect of immunoglobulin G (IgG) interchain disulfide bond cleavage on efficacy of intravenous immunoglobulin for immune thrombocytopenic purpura (ITP)

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