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Bioengineered bugs expressing oligosaccharide receptor mimics: Toxin-binding probiotics for treatment and prevention of enteric infections

Many microbial pathogens recognize oligosaccharides displayed on the surface of host cells as receptors for toxins and adhesins. These ligand-receptor interactions are critical for disease pathogenesis, making them promising targets for novel anti-infectives. One strategy with particular utility aga...

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Autori principali: Paton, Adrienne W, Morona, Renato, Paton, James C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026422/
https://ncbi.nlm.nih.gov/pubmed/21326923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.3.10665
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