Oral Administration of Formaldehyde-Killed Recombinant Bacteria Expressing a Mimic of the Shiga Toxin Receptor Protects Mice from Fatal Challenge with Shiga-Toxigenic Escherichia coli

Gastrointestinal disease caused by Shiga toxin-producing Escherichia coli (STEC) is frequently complicated by life-threatening toxin-induced systemic sequelae, including the hemolytic uremic syndrome. We previously constructed a recombinant bacterium displaying a Shiga toxin receptor mimic on its su...

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Detalhes bibliográficos
Main Authors: Paton, James C., Rogers, Trisha J., Morona, Renato, Paton, Adrienne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98032/
https://ncbi.nlm.nih.gov/pubmed/11179303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1389-1393.2001
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