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Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development
Pancreatic organogenesis is promoted or restricted by different signaling pathways. In amniotes, inhibition of hedgehog (Hh) activity in the early embryonic endoderm is a prerequisite for pancreatic specification. However, in zebrafish, loss of Hh signaling leads to a severe reduction of β-cells, le...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Company of Biologists
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026410/ https://ncbi.nlm.nih.gov/pubmed/21228001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.050450 |
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