SMOC can act as both an antagonist and an expander of BMP signaling

The matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically from vertebrates to arthropods. We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of its receptor via activation of mitogen-activated protein kinase (MA...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Thomas, J Terrig, Eric Dollins, D, Andrykovich, Kristin R, Chu, Tehyen, Stultz, Brian G, Hursh, Deborah A, Moos, Malcolm
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360445/
https://ncbi.nlm.nih.gov/pubmed/28323621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17935
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