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Roles of Hedgehog pathway components and retinoic acid signalling in specifying zebrafish ventral spinal cord neurons
In mouse, Hedgehog (Hh) signalling is required for most ventral spinal neurons to form. Here, we analyse the spinal cord phenotype of zebrafish maternal-zygotic smoothened (MZsmo) mutants that completely lack Hh signalling. We find that most V3 domain cells and motoneurons are lost, whereas medial f...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Company of Biologists
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210494/ https://ncbi.nlm.nih.gov/pubmed/22069186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066159 |
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