Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach

The heterogeneity and instability of human tumors hamper straightforward identification of cancer-causing mutations through genomic approaches alone. Herein we describe a mouse model of liver cancer initiated from progenitor cells harboring defined cancer-predisposing lesions. Genome-wide analyses o...

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Main Authors: Zender, Lars, Spector, Mona S., Xue, Wen, Flemming, Peer, Cordon-Cardo, Carlos, Silke, John, Fan, Sheung-Tat, Luk, John M., Wigler, Michael, Hannon, Gregory J., Mu, David, Lucito, Robert, Powers, Scott, Lowe, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026384/
https://ncbi.nlm.nih.gov/pubmed/16814713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.05.030
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