The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population

BACKGROUND: The BRCA1 and BRCA2 mutation spectrum and mutation detection rates according to different family histories were investigated in 521 subjects from 322 unrelated Slovenian cancer families with breast and/or ovarian cancer. METHODS: The BRCA1 and BRCA2 genes were screened using DGGE, PTT, H...

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Main Authors: Stegel, Vida, Krajc, Mateja, Žgajnar, Janez, Teugels, Erik, De Grève, Jacques, Hočevar, Marko, Novaković, Srdjan
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025939/
https://ncbi.nlm.nih.gov/pubmed/21232165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-9
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