The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population

BACKGROUND: The BRCA1 and BRCA2 mutation spectrum and mutation detection rates according to different family histories were investigated in 521 subjects from 322 unrelated Slovenian cancer families with breast and/or ovarian cancer. METHODS: The BRCA1 and BRCA2 genes were screened using DGGE, PTT, H...

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Autores principales: Stegel, Vida, Krajc, Mateja, Žgajnar, Janez, Teugels, Erik, De Grève, Jacques, Hočevar, Marko, Novaković, Srdjan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025939/
https://ncbi.nlm.nih.gov/pubmed/21232165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-9
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