Cytology material is equivalent to tumor tissue in determining mutations of BRCA 1/2 genes in patients with tubo-ovarian high grade serous carcinoma

BACKGROUND: High-grade serous ovarian cancer is a detrimental disease. Treatment options in patients with a recurrent disease are dependent on BRCA1/2 mutation status since only patients with known BRCA mutation are eligible for treatment with poly(ADP-ribose) polymerase inhibitors (PARPi). The aim...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gornjec, Andreja, Novakovic, Srdjan, Stegel, Vida, Hocevar, Marko, Pohar Marinsek, Ziva, Gazic, Barbara, Krajc, Mateja, Skof, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444857/
https://ncbi.nlm.nih.gov/pubmed/30940100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5535-2
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