Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

In Duchenne muscular dystrophy (DMD), dystrophin mutation leads to progressive lethal skeletal muscle degeneration. For unknown reasons, dystrophin deficiency does not recapitulate DMD in mice (mdx), which have mild skeletal muscle defects and potent regenerative capacity. We postulated that human D...

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Hlavní autoři: Sacco, Alessandra, Mourkioti, Foteini, Tran, Rose, Choi, Jinkuk, Llewellyn, Michael, Kraft, Peggy, Shkreli, Marina, Delp, Scott, Pomerantz, Jason H., Artandi, Steven E., Blau, Helen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025608/
https://ncbi.nlm.nih.gov/pubmed/21145579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.11.039
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