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Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube.

Mice genetically deficient for the telomerase RNA (mTR) can be propagated for only a limited number of generations. In particular, mTR-/- mice of a mixed C57BL6/129Sv genetic background are infertile at the sixth generation and show serious hematopoietic defects. Here, we show that a percentage of m...

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Bibliografski detalji
Glavni autori: Herrera, E, Samper, E, Blasco, M A
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171208/
https://ncbi.nlm.nih.gov/pubmed/10064584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.5.1172
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