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Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube.
Mice genetically deficient for the telomerase RNA (mTR) can be propagated for only a limited number of generations. In particular, mTR-/- mice of a mixed C57BL6/129Sv genetic background are infertile at the sixth generation and show serious hematopoietic defects. Here, we show that a percentage of m...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171208/ https://ncbi.nlm.nih.gov/pubmed/10064584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.5.1172 |
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