Role of Telomere Dysfunction in Cardiac Failure in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD), the most common inherited muscular dystrophy of childhood, leads to death due to cardiorespiratory failure. Paradoxically, mdx mice with the same genetic deficiency of dystrophin, exhibit minimal cardiac dysfunction, impeding the development of therapies. We postul...

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Hlavní autoři: Mourkioti, Foteini, Kustan, Jackie, Kraft, Peggy, Day, John W., Zhao, Ming-Ming, Kost-Alimova, Maria, Protopopov, Alexei, DePinho, Ronald A., Bernstein, Daniel, Meeker, Alan K., Blau, Helen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774175/
https://ncbi.nlm.nih.gov/pubmed/23831727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2790
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