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Role of Telomere Dysfunction in Cardiac Failure in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD), the most common inherited muscular dystrophy of childhood, leads to death due to cardiorespiratory failure. Paradoxically, mdx mice with the same genetic deficiency of dystrophin, exhibit minimal cardiac dysfunction, impeding the development of therapies. We postul...

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Detalhes bibliográficos
Main Authors: Mourkioti, Foteini, Kustan, Jackie, Kraft, Peggy, Day, John W., Zhao, Ming-Ming, Kost-Alimova, Maria, Protopopov, Alexei, DePinho, Ronald A., Bernstein, Daniel, Meeker, Alan K., Blau, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774175/
https://ncbi.nlm.nih.gov/pubmed/23831727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2790
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