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Drug-Metabolizing Enzyme, Transporter and Nuclear Receptor Genetically Modified Mouse Models
Determining the in vivo significance of a specific enzyme, transporter or xenobiotic receptor in drug metabolism and pharmacokinetics may be hampered by gene multiplicity and complexity, levels of expression and interaction between various components involved. The development of knockout (loss-of-fu...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025535/ https://ncbi.nlm.nih.gov/pubmed/20854191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602532.2010.512294 |
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