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Drug-Metabolizing Enzyme, Transporter and Nuclear Receptor Genetically Modified Mouse Models
Determining the in vivo significance of a specific enzyme, transporter or xenobiotic receptor in drug metabolism and pharmacokinetics may be hampered by gene multiplicity and complexity, levels of expression and interaction between various components involved. The development of knockout (loss-of-fu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025535/ https://ncbi.nlm.nih.gov/pubmed/20854191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602532.2010.512294 |
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