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Pathophysiology of motility dysfunction in bowel obstruction: role of stretch-induced COX-2

In gastrointestinal conditions such as bowel obstruction, pseudo-obstruction, and idiopathic megacolon, the lumen of affected bowel segments is distended and its motility function impaired. Our hypothesis is that mechanical stretch of the distended segments alters gene expression of cyclooxygenase-2...

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Bibliografiske detaljer
Main Authors: Shi, Xuan-Zheng, Lin, You-Min, Powell, Don W., Sarna, Sushil K.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025501/
https://ncbi.nlm.nih.gov/pubmed/21051526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00379.2010
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