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Pathophysiology of motility dysfunction in bowel obstruction: role of stretch-induced COX-2

In gastrointestinal conditions such as bowel obstruction, pseudo-obstruction, and idiopathic megacolon, the lumen of affected bowel segments is distended and its motility function impaired. Our hypothesis is that mechanical stretch of the distended segments alters gene expression of cyclooxygenase-2...

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Detalhes bibliográficos
Main Authors: Shi, Xuan-Zheng, Lin, You-Min, Powell, Don W., Sarna, Sushil K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025501/
https://ncbi.nlm.nih.gov/pubmed/21051526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00379.2010
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