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Cellular mechanism of mechanotranscription in colonic smooth muscle cells
Mechanical stretch in obstruction induces expression of cyclooxygenase-2 (COX-2) in gut smooth muscle cells (SMCs). The stretch-induced COX-2 plays a critical role in motility dysfunction in obstructive bowel disorders (OBDs). The aims of the present study were to investigate the intracellular mecha...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468553/ https://ncbi.nlm.nih.gov/pubmed/22700825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00440.2011 |
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