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Cellular mechanism of mechanotranscription in colonic smooth muscle cells
Mechanical stretch in obstruction induces expression of cyclooxygenase-2 (COX-2) in gut smooth muscle cells (SMCs). The stretch-induced COX-2 plays a critical role in motility dysfunction in obstructive bowel disorders (OBDs). The aims of the present study were to investigate the intracellular mecha...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468553/ https://ncbi.nlm.nih.gov/pubmed/22700825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00440.2011 |
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