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A condensed view of chromatin during T cell development

The mechanisms limiting clonal T-cell expansion in response to cytokines to cells that have recognised cognate antigen via their T-cell receptor are incompletely understood. A study by Rawlings et al identifies one such mechanism that functions, unexpectedly, through chromatin compaction and involve...

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Autori principali: Wood, Andrew J, Bickmore, Wendy A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025473/
https://ncbi.nlm.nih.gov/pubmed/21245890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.340
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