TDP-43 regulates its mRNA levels through a negative feedback loop

TAR DNA-binding protein (TDP-43) is an evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) involved in RNA processing, whose abnormal cellular distribution and post-translational modification are key markers of certain neurodegenerative diseases, such as amyotrophic lateral scle...

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Hlavní autoři: Ayala, Youhna M, De Conti, Laura, Avendaño-Vázquez, S Eréndira, Dhir, Ashish, Romano, Maurizio, D'Ambrogio, Andrea, Tollervey, James, Ule, Jernej, Baralle, Marco, Buratti, Emanuele, Baralle, Francisco E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025456/
https://ncbi.nlm.nih.gov/pubmed/21131904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.310
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