Tumor Response and Progression-Free Survival as Potential Surrogate Endpoints for Overall Survival in Extensive-Stage Small Cell Lung Cancer (ES-SCLC): Findings Based on North Central Cancer Treatment Group (NCCTG) Trials

PURPOSE: We investigated the putative surrogate endpoints (PSEs) of best response (BR), complete response (CR), confirmed response (CoR), and progression-free survival (PFS) for associations with Overall Survival (OS), and as possible surrogate endpoints for OS. METHODS: Individual patient (pt) data...

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Autori principali: Foster, Nathan R., Qi, Yingwei, Shi, Qian, Krook, James E., Kugler, John W., Jett, James R., Molina, Julian R., Schild, Steven E., Adjei, Alex A., Mandrekar, Sumithra J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025267/
https://ncbi.nlm.nih.gov/pubmed/20960500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25526
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