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Pim3 negatively regulates glucose-stimulated insulin secretion

Pancreatic β-cell response to glucose stimulation is governed by tightly regulated signaling pathways which have not been fully characterized. A screen for novel signaling intermediates identified Pim3 as a glucose-responsive gene in the β-cell, and here, we characterize its role in the regulation o...

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Main Authors: Vlacich, Gregory, Nawijn, Martijn C, Webb, Gene C, Steiner, Donald F
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025049/
https://ncbi.nlm.nih.gov/pubmed/21099329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.2.5.13058
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