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Pim3 negatively regulates glucose-stimulated insulin secretion
Pancreatic β-cell response to glucose stimulation is governed by tightly regulated signaling pathways which have not been fully characterized. A screen for novel signaling intermediates identified Pim3 as a glucose-responsive gene in the β-cell, and here, we characterize its role in the regulation o...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025049/ https://ncbi.nlm.nih.gov/pubmed/21099329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.2.5.13058 |
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