Insulin enhances glucose-stimulated insulin secretion in healthy humans

Islet β-cells express both insulin receptors and insulin-signaling proteins. Recent evidence from rodents in vivo and from islets isolated from rodents or humans suggests that the insulin signaling pathway is physiologically important for glucose sensing. We evaluated whether insulin regulates β-cel...

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Hauptverfasser: Bouche, Clara, Lopez, Ximena, Fleischman, Amy, Cypess, Aaron M., O'Shea, Sheila, Stefanovski, Darko, Bergman, Richard N., Rogatsky, Eduard, Stein, Daniel T., Kahn, C. Ronald, Kulkarni, Rohit N., Goldfine, Allison B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842068/
https://ncbi.nlm.nih.gov/pubmed/20176932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000002107
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