PLK1 Phosphorylates Mitotic Centromere-associated Kinesin and Promotes Its Depolymerase Activity

During cell division, interaction between kinetochores and dynamic spindle microtubules governs chromosome movements. The microtubule depolymerase mitotic centromere-associated kinesin (MCAK) is a key regulator of mitotic spindle assembly and dynamics. However, the regulatory mechanisms underlying i...

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Hlavní autoři: Zhang, Liangyu, Shao, Hengyi, Huang, Yuejia, Yan, Feng, Chu, Youjun, Hou, Hai, Zhu, Mei, Fu, Chuanhai, Aikhionbare, Felix, Fang, Guowei, Ding, Xia, Yao, Xuebiao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024797/
https://ncbi.nlm.nih.gov/pubmed/21078677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165340
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