Signaling-dependent Phosphorylation of Mitotic Centromere-associated Kinesin Regulates Microtubule Depolymerization and Its Centrosomal Localization

Although p21-activated kinase 1 (PAK1) and microtubule (MT) dynamics regulate numerous fundamental processes including cytoskeleton remodeling, directional motility, and mitotic functions, the significance of PAK1 signaling in regulating the functions of MT-destabilizing protein mitotic centromere-a...

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Autors principals: Pakala, Suresh B., Nair, Vasudha S., Reddy, Sirigiri DivijendraNatha, Kumar, Rakesh
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504770/
https://ncbi.nlm.nih.gov/pubmed/23055517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399576
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