LPS Impairs Phospholipid Synthesis by Triggering β-Transducin Repeat-containing Protein (β-TrCP)-mediated Polyubiquitination and Degradation of the Surfactant Enzyme Acyl-CoA:Lysophosphatidylcholine Acyltransferase I (LPCAT1)

Acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1) is a relatively newly described and yet indispensable enzyme needed for generation of the bioactive surfactant phospholipid, dipalmitoylphosphatidylcholine (DPPtdCho). Here, we show that lipopolysaccharide (LPS) causes LPCAT1 degradation us...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zou, Chunbin, Butler, Phillip L., Coon, Tiffany A., Smith, Rebecca M., Hammen, Gary, Zhao, Yutong, Chen, Bill B., Mallampalli, Rama K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2011
विषय:
Lipids
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024768/
https://ncbi.nlm.nih.gov/pubmed/21068446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192377
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