Acyl-CoA:Lysophosphatidylcholine Acyltransferase I (Lpcat1) Catalyzes Histone Protein O-Palmitoylation to Regulate mRNA Synthesis

The enzyme acyl-CoA:lysophosphatidylcholine acyltransferase (Lpcat1) is a critical cytosolic enzyme needed for lung surfactant synthesis that catalyzes an acyltransferase reaction by adding a palmitate to the sn-2 position of lysophospholipids. Here we report that histone H4 protein is subject to pa...

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Main Authors: Zou, Chunbin, Ellis, Bryon M., Smith, Rebecca M., Chen, Bill B., Zhao, Yutong, Mallampalli, Rama K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151047/
https://ncbi.nlm.nih.gov/pubmed/21685381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253385
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