Cell-permeable Carboxyl-terminal p27(Kip1) Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 Kinase

The incidence and death rate of prostate cancer is increasing rapidly. In addition, the low sensitivity of prostate cancer to chemotherapy makes it difficult to treat this condition. The serine/threonine kinase Pim-1 plays an important role in cell cycle progression and apoptosis inhibition, resulti...

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Autors principals: Morishita, Daisuke, Takami, Miho, Yoshikawa, Seiko, Katayama, Ryohei, Sato, Shigeo, Kukimoto-Niino, Mutsuko, Umehara, Takashi, Shirouzu, Mikako, Sekimizu, Kazuhisa, Yokoyama, Shigeyuki, Fujita, Naoya
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024764/
https://ncbi.nlm.nih.gov/pubmed/21062737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092452
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