Cell-permeable Carboxyl-terminal p27(Kip1) Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 Kinase

The incidence and death rate of prostate cancer is increasing rapidly. In addition, the low sensitivity of prostate cancer to chemotherapy makes it difficult to treat this condition. The serine/threonine kinase Pim-1 plays an important role in cell cycle progression and apoptosis inhibition, resulti...

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Bibliographische Detailangaben
Hauptverfasser: Morishita, Daisuke, Takami, Miho, Yoshikawa, Seiko, Katayama, Ryohei, Sato, Shigeo, Kukimoto-Niino, Mutsuko, Umehara, Takashi, Shirouzu, Mikako, Sekimizu, Kazuhisa, Yokoyama, Shigeyuki, Fujita, Naoya
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024764/
https://ncbi.nlm.nih.gov/pubmed/21062737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092452
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