The Coactivator SRC-1 is an Essential Coordinator of Hepatic Glucose Production

Gluconeogenesis makes a major contribution to hepatic glucose production, a process critical for survival in mammals. In this study, we identify the p160 family member, SRC-1, as a key coordinator of the hepatic gluconeogenic program in vivo. SRC-1 null mice displayed hypoglycemia secondary to a def...

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Main Authors: Louet, Jean-Francois, Chopra, Atul R., Sagen, Jorn V., An, Jie, York, Brian, Tannour-Louet, Mounia, Saha, Pradip K., Stevens, Robert D., Wenner, Brett R., Ilkayeva, Olga R., Bain, James R., Zhou, Suoling, DeMayo, Franco, Xu, Jianming, Newgard, Christopher B., O'Malley, Bert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024581/
https://ncbi.nlm.nih.gov/pubmed/21109193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.11.009
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