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Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection

Improved understanding of the dynamics of host immune responses and viral evolution is critical for effective HIV-1 vaccine design. We comprehensively analyzed Cytotoxic T-lymphocyte (CTL)-viral epitope dynamics in an antiretroviral therapy-naïve subject over the first four years of HIV-1 infection....

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Detalhes bibliográficos
Main Authors: Liu, Yi, McNevin, John P., Holte, Sarah, McElrath, M. Juliana, Mullins, James I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024315/
https://ncbi.nlm.nih.gov/pubmed/21283794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015639
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