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Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress

BACKGROUND: Sox9 (Sry box containing gene 9) is a DNA-binding transcription factor involved in chondrocyte development and sex determination. The protein's absence in testicular Sertoli nurse cells has been shown to disrupt testicular function in adults but little is known at the genome-wide le...

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Main Authors: Lardenois, Aurélie, Chalmel, Frédéric, Barrionuevo, Francisco, Demougin, Philippe, Scherer, Gerd, Primig, Michael
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024295/
https://ncbi.nlm.nih.gov/pubmed/21182756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-8-154
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