Fhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression

BACKGROUND: The LIM domain protein Fhl5 was previously found to interact with CREM, a DNA binding transcriptional regulator necessary for spermiogenesis in mammals. Co-transfection experiments using heterologous promoter constructs indicated a role for Fhl5 in transcriptional up-regulation of CREM-d...

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Bibliografiska uppgifter
Huvudupphovsmän: Lardenois, Aurélie, Chalmel, Frédéric, Demougin, Philippe, Kotaja, Noora, Sassone-Corsi, Paolo, Primig, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2009
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788571/
https://ncbi.nlm.nih.gov/pubmed/19930692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-7-133
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