Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene

ACT [activator of cAMP-responsive element modulator (CREM) in testis] is a LIM-only protein that interacts with transcription factor CREM in postmeiotic male germ cells and enhances CREM-dependent transcription. CREM regulates many crucial genes required for spermatid maturation, and targeted mutati...

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Autori principali: Kotaja, Noora, De Cesare, Dario, Macho, Betina, Monaco, Lucia, Brancorsini, Stefano, Goossens, Ellen, Tournaye, Herman, Gansmuller, Anne, Sassone-Corsi, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC489983/
https://ncbi.nlm.nih.gov/pubmed/15247423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401947101
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